Optimal design of radiation compensators.
Optimal design of radiation compensators.
复制标题
辐射补偿器的优化设计。
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
M. E. Hale
中科院分区：
文献类型：
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作者：
A. Djordjevich;D. J. Bonham;E. M. A. Hussein;J. W. Andrew;M. E. Hale
提出了一种实现多波束情况下放射治疗补偿滤波器优化设计的方法。优化剂量分布，使其在目标区接近规定值，在其他地方最小化，在脆弱区域不超过指定限值。场的形状、大小和重量，以及考虑到缺失组织和身体异质性的过滤器厚度，都是这个过程的结果。并对计算出的滤光片和光束应用后的剂量分布进行了预测。该方法是严格的，其准确性仅取决于所应用剂量计算方法的准确性。利用Theraplan 300L治疗计划系统的数据对实例进行了讨论和验证。
A method to achieve the optimal design of radiation therapy compensating filters in multibeam situations is proposed. Dose distribution is optimized such that it approaches the prescribed value in the target zone, is minimized everywhere else, and does not exceed designated limits at vulnerable regions. Field shapes, sizes, and weights, together with filter thicknesses that take into account missing tissues and body heterogeneities, are calculated as a result of this process. The dose distribution, after the application of the calculated filters and beams, is also predicted. The method is rigorous, and its accuracy depends only upon the accuracy of the applied dose calculation method. Examples are discussed and verified using data obtained from Theraplan 300L treatment planning system.