Globularity and language-readiness: generating new predictions by expanding the set of genes of interest.

Globularity and language-readiness: generating new predictions by expanding the set of genes of interest.
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DOI:
10.3389/fpsyg.2014.01324
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发表时间:
2014
影响因子:
3.8
通讯作者:
Benítez-Burraco A
Benítez-Burraco A
中科院分区:
心理学3区
文献类型:
--
作者:
Boeckx C;Benítez-Burraco A

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这项研究建立在提出的假设的基础上,根据该假设,在大脑形态和神经连接水平上表达的发育变化导致我们物种的脑壳变得更加球形,这对于理解我们准备语言的大脑的起源至关重要。具体来说,本文探讨了两个著名的“语言相关”基因(如与声音学习有关的 FOXP2 和 ROBO1)与最初提出的一组感兴趣基因(以 RUNX2 为焦点)之间的联系。依靠现有的文献,我们发现了潜在的分子联系,这些联系可能对未来对语言生物学基础的实验研究和对我们最初假设的检验感兴趣。我们的讨论也可能与临床语言学和古基因组学结果的解释相关。
This study builds on the hypothesis put forth in, according to which the developmental changes expressed at the levels of brain morphology and neural connectivity that resulted in a more globular braincase in our species were crucial to understand the origins of our language-ready brain. Specifically, this paper explores the links between two well-known ‘language-related’ genes like FOXP2 and ROBO1 implicated in vocal learning and the initial set of genes of interest put forth in, with RUNX2 as focal point. Relying on the existing literature, we uncover potential molecular links that could be of interest to future experimental inquiries into the biological foundations of language and the testing of our initial hypothesis. Our discussion could also be relevant for clinical linguistics and for the interpretation of results from paleogenomics.
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发表时间: 2006-06-01
期刊: DEVELOPMENT
影响因子: 4.6
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