Longitudinal differences in disease specific quality of life in men with erectile dysfunction: Results from the exploratory comprehensive evaluation of erectile dysfunction study

Longitudinal differences in disease specific quality of life in men with erectile dysfunction: Results from the exploratory comprehensive evaluation of erectile dysfunction study
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DOI:
10.1097/01.ju.0000049203.33463.9e
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发表时间:
2003-04-01
期刊:
影响因子:
6.6
通讯作者:
Lue, TF
Lue, TF
中科院分区:
医学1区
文献类型:
--
作者:
Latini, DM;Penson, DF;Lue, TF

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Purpose: We assessed the impact of erectile dysfunction therapy on 1-year health related quality of life using a validated erectile dysfunction specific instrument.Materials and Methods: Using an observational erectile dysfunction registry clinical, sociodemographic and health related quality of life information was collected at baseline, and 3, 6 and 12 months later. Only men who reported undergoing erectile dysfunction treatment were included in this analysis sub-sample. Patients were classified as treatment responders based on improvements in International Index of Erectile Function scores. Changes in health related quality of life scores from baseline were compared between responders and nonresponders.Results: The cohort consisted of 89 patients, of whom 40 (45%) responded to therapy by International Index of Erectile Function criteria. Responders and nonresponders had comparable baseline disease severity and health related quality of life. At 1 year responders reported significantly better health related quality of life and greater improvement from baseline in sexual experience (mean change -1.64 versus 3.19) and emotional life (mean -3.01 for responders versus 1.75) domains of the Psychological Impact of Erectile Dysfunction scales (p