SOCE in the cardiomyocyte: the secret is in the chambers.

SOCE in the cardiomyocyte: the secret is in the chambers.
复制标题

心肌细胞中的SOCE:秘密就在心室中。

DOI:
10.1007/s00424-021-02540-3
复制
发表时间:
2021-03
期刊:
Pflugers Archiv : European journal of physiology
影响因子:
--
通讯作者:
Wang C
Wang C
中科院分区:
其他
文献类型:
--
作者:
Rosenberg P;Zhang H;Bryson VG;Wang C

文献摘要

参考文献

被引文献

相似文献

钙池操纵的 Ca2+ 进入 (SOCE) 是一种古老且普遍存在的 Ca2+ 信号通路,几乎存在于每种细胞类型中。在过去的二十年中,许多研究表明这种非电压依赖性 Ca2+ 进入途径与心脏生理学有关。鉴于兴奋收缩耦合的明确作用,心肌细胞中 SOCE 通路的相关性经常受到质疑。在这篇综述中,我们考虑了 STIM1 和 SOCE 有助于心肌细胞 Ca2+ 动态的证据。我们讨论了这条通路与心脏生长响应发育和病理线索的相关性。我们还探讨了 STIM1 是否有助于 Ca2+ 储存再填充,从而可能影响心肌细胞的心脏起搏和心律失常发生。
Store-operated Ca2+ entry (SOCE) is an ancient and ubiquitous Ca2+ signaling pathway that is present in virtually every cell type. Over the last two decades, many studies have implicated this non-voltage dependent Ca2+ entry pathway in cardiac physiology. The relevance of the SOCE pathway in cardiomyocytes is often questioned given the well-established role for excitation contraction coupling. In this review, we consider the evidence that STIM1 and SOCE contribute to Ca2+ dynamics in cardiomyocytes. We discuss the relevance of this pathway to cardiac growth in response to developmental and pathologic cues. We also address whether STIM1 contributes to Ca2+ store refilling that likely impacts cardiac pacemaking and arrhythmogenesis in cardiomyocytes.
DOI: 10.1074/jbc.m115.684076
发表时间: 2015-12-11
期刊: The Journal of biological chemistry
影响因子: --
作者:
Capel RA;Bolton EL;Lin WK;Aston D;Wang Y;Liu W;Wang X;Burton RA;Bloor-Young D;Shade KT;Ruas M;Parrington J;Churchill GC;Lei M;Galione A;Terrar DA
通讯作者: Terrar DA
DOI: 10.1038/s41598-017-14134-0
发表时间: 2017-10-27
期刊: Scientific reports
影响因子: 4.6
作者:
Boncompagni S;Michelucci A;Pietrangelo L;Dirksen RT;Protasi F
通讯作者: Protasi F
DOI: 10.1016/j.nmd.2017.05.002
发表时间: 2017-09-01
影响因子: 2.8
作者:
Harris, Elizabeth;Burki, Umar;Barresi, Rita
通讯作者: Barresi, Rita
DOI: 10.1111/j.1600-065x.2009.00818.x
发表时间: 2009-09
影响因子: 8.7
作者:
通讯作者: --
DOI: 10.1152/ajpheart.00075.2014
发表时间: 2014-04-01
影响因子: 4.8
作者:
Collins, Helen E.;He, Lan;Chatham, John C.
通讯作者: Chatham, John C.