Mechanical properties of porcine femoral cortical bone measured by nanoindentation
Mechanical properties of porcine femoral cortical bone measured by nanoindentation
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DOI：
10.1016/j.jbiomech.2012.05.001
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发表时间：
2012-06-26
影响因子：
2.4
通讯作者：
Jasiuk, Iwona
中科院分区：
文献类型：
--
作者：
Feng, Liang;Chittenden, Michael;Jasiuk, Iwona
本研究使用纳米压痕技术，以检查在猪股骨皮质骨的局部力学性能的变化在水合条件下。对来自三个年龄组（6、12和42个月）的骨样本（代表发育中的骨，范围从年轻到成熟动物）的纵向和横向横截面进行了测试。测量了骨微观结构中单个骨板的弹性模量和硬度：骨板、间质骨和骨单位。弹性模量和硬度均随老化而增加。然而，这些增加的幅度是不同的每个微观结构组件。纵向弹性模量高于横向弹性模量。还测试了脱水样品以允许与水合样品进行比较，并且这些导致比水合样品更高的模量和硬度。同样，每个微观结构组分的变化程度不同。这些结果表明，在骨的发育变化有不同的速率内的每个微观结构组件的机械变化。(C)2012爱思唯尔有限公司保留所有权利。
This study uses a nanoindentation technique to examine variations in the local mechanical properties of porcine femoral cortical bone under hydrated conditions. Bone specimens from three age groups (6, 12 and 42 months), representing developing bone, ranging from young to mature animals, were tested on the longitudinal and transverse cross-sectional surfaces. Elastic modulus and hardness of individual lamellae within bone's microstructure: laminar bone, interstitial bone, and osteons, were measured. Both the elastic modulus and hardness increased with age. However, the magnitudes of these increases were different for each microstructural component. The longitudinal moduli were higher than the transverse moduli. Dehydrated samples were also tested to allow a comparison with hydrated samples and these resulted in higher moduli and hardness than the hydrated samples. Again, the degree of variation was different for each microstructural component. These results indicate that the developmental changes in bone have different rates of mechanical change within each microstructural component. (C) 2012 Elsevier Ltd. All rights reserved.