Detrusor sphincter dyssynergia: can a more specific definition distinguish between patients with and without an underlying neurological disorder?

Detrusor sphincter dyssynergia: can a more specific definition distinguish between patients with and without an underlying neurological disorder?
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逼尿肌括约肌协同障碍:更具体的定义能否区分有或无潜在神经系统疾病的患者?

DOI:
10.1038/s41393-021-00635-3
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发表时间:
2021-09
期刊:
影响因子:
2.2
通讯作者:
Kessler TM
Kessler TM
中科院分区:
医学3区
文献类型:
--
作者:
Gross O;Leitner L;Rasenack M;Schubert M;Kessler TM

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横断面研究。评估逼尿肌括约肌协同失调(DSD)的特定定义是否可以区分脊髓损伤(SCI)和无潜在神经系统疾病(NO ND)的个体。单一大专院校SCI中心。一系列的153人,81例创伤性SCI和72例无ND,进行了前瞻性评估,并纳入本研究。所有受试者均接受了临床神经泌尿系统检查、神经生理学检查和视频尿动力学检查,并被诊断为国际尿失禁协会(ICS)定义的DSD。我们根据Yalla(1-3级)、Blaivas(1-3型)和Weld(1-2型)的分类确定了DSD等级/类型。比较SCI和NO ND患者的DSD分级/类型分布。评估了各种DSD等级/类型与临床参数之间的相关性,如上尿路损伤(所有个体)或下肢运动评分的风险因素、SCI损伤水平和严重程度评分(仅SCI组)。所有DSD类型的分布组间相似(p > 0.05)。DSD分类均不允许对上尿路损伤进行风险评估。DSD类型与其他临床参数之间无显著相关性(p > 0.05)。没有一个被调查的DSD定义可以区分SCI患者和NO ND患者。Yalla、Blaivas或Weld提出的更复杂的DSD分类无法与ICS二元是非定义相竞争,后者在日常临床实践中管理患者时实用且简单。没有。
Cross-sectional study. To evaluate if specific definitions of detrusor sphincter dyssynergia (DSD) might distinguish between individuals with spinal cord injury (SCI) and those with no underlying neurological disorder (NO ND). Single tertiary university SCI center. A series of 153 individuals, 81 with traumatic SCI and 72 with NO ND, were prospectively evaluated and included in this study. All individuals underwent a clinical neuro-urological examination, a neurophysiological work-up and a video-urodynamic investigation and were diagnosed with DSD as defined by the International Continence Society (ICS). We determined the DSD grades/types according to the classifications by Yalla (grade 1–3), Blaivas (type 1–3) and Weld (type 1–2). Distribution of the DSD grades/types were compared between SCI and NO ND individuals. Associations between the various DSD grades/types and clinical parameters, such as risk factors for upper urinary tract damage (all individuals) or lower extremity motor scores, SCI injury levels and severity scores (only SCI group), were assessed. The distribution of all DSD types were similar between groups (p > 0.05). None of the DSD classifications allowed risk assessment for upper urinary tract damage. A significant association between DSD type and other clinical parameters could not be found (p > 0.05). None of the investigated DSD definitions can distinguish between patients with SCI and with NO ND. The more complex DSD classifications by Yalla, Blaivas or Weld cannot compete with the ICS binary yes-no definition which is pragmatic and straightforward for managing patients in daily clinical practice. None.
会阴表面肌电图通常不会在正常空隙过程中表现出预期的松弛。
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