Fast potentiation of glycine receptor channels by intracellular calcium in neurons and transfected cells
Fast potentiation of glycine receptor channels by intracellular calcium in neurons and transfected cells
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DOI：
10.1016/s0896-6273(00)00134-3
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发表时间：
2000-11-01
期刊：
影响因子：
16.2
通讯作者：
Bregestovski, P
中科院分区：
文献类型：
--
作者：
Fucile, S;De Saint Jan, D;Bregestovski, P
抑制性甘氨酸受体（GlyR）主要在脊髓和中脑中表达，在那里它们控制运动和感觉通路。我们在这里描述了细胞内Ca 2+对GlyR的快速增强作用。在大鼠脊髓神经元和转染的人细胞系中观察到这种现象。增强发展在
Inhibitory glycine receptors (GlyRs) are mainly expressed in the spinal cord and in the midbrain, where they control motor and sensory pathways. We describe here a fast potentiation of GlyR by intracellular Ca2+. This phenomenon was observed in rat spinal cord neurons and in transfected human cell lines. Potentiation develops in