Catheter thrombosis
Catheter thrombosis
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DOI：
10.1046/j.1525-139x.2001.00109.x
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发表时间：
2001-11-01
影响因子：
1.6
通讯作者：
Beathard, GA
中科院分区：
文献类型：
--
作者：
Beathard, GA
由于流动不良导致的导管故障是常见问题。如果发生在早期，原因通常是技术性的。晚期发生最常与血栓形成有关。可以看到几种类型的血栓，根据位置和假定的形成机制而不同。然而，最常见的罪犯是纤维蛋白鞘血栓。预防导管故障是一项奋进，继续提出许多问题。导管故障应及早处理，以避免透析不充分。在过去，尿激酶是一个非常有价值的援助肾病学家在管理这个问题。自从这种药剂无法使用以来，还没有出现合适的替代品。重组组织纤溶酶原激活剂（tPA）似乎是最有可能发挥这一作用的候选者;然而，目前还没有最适合此目的的包装形式。目前。导管交换似乎是解决这个问题的最佳可选择方案，这个问题还不能通过更简单的手段来解决。
Catheter malfunction due to poor flow is a common problem. When it occurs early, the cause is generally technical. Late occurrences are most often related to thrombus formation. Several types of thrombus may be seen, differing by location and supposed mechanism of formation. The most common offender, however, is the fibrin sheath thrombus. Prevention of catheter malfunction is an endeavor that continues to beg many questions. Catheter malfunction should be treated early to avoid inadequate dialysis. In the past, urokinase was a highly valuable aid to the nephrologist in managing this problem. Since this agent became unavailable a suitable alternative has not emerged. Recombinant tissue plasminogen activator (tPA) seems to be the most likely candidate for this role; however, it is not currently available in a packaging form that is optimal for this purpose. Currently. catheter exchange appears to be the best available alternative for this problem, which cannot yet be resolved by simpler means.