Nanoparticle-Biological Interactions in a Marine Benthic Foraminifer
Nanoparticle-Biological Interactions in a Marine Benthic Foraminifer
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DOI：
10.1038/s41598-019-56037-2
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发表时间：
2019-12-19
影响因子：
4.6
通讯作者：
Frontalini, Fabrizio
中科院分区：
文献类型：
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作者：
Ciacci, Caterina;Grimmelpont, Margot, V;Frontalini, Fabrizio
工程纳米材料（ENM）在海洋环境中的不利影响最近引起了极大的关注，但其对有孔虫等海洋底栖生物的影响在很大程度上仍被忽视。在这里，我们记录了三个带负电荷的ENM，不同的大小和组成，二氧化钛（TiO 2），聚苯乙烯（PS）和二氧化硅（SiO 2），对微生物真核生物（底栖有孔虫氨parkinsoniana）使用多种方法的影响。这项研究清楚地表明，有孔虫细胞质内，金属（Ti）和有机（PS）ENM，促进生理应激的存在。具体而言，显着增加中性脂质的积累和增强活性氧的生产发生在ENM处理的标本，无论ENM类型。这项研究表明，ENM代表这种微生物真核生物的生态毒理学风险，并提出了一个新的模式，被忽视的海洋底栖生物，以评估自然暴露的情况。
The adverse effects of engineered nanomaterials (ENM) in marine environments have recently attracted great attention although their effects on marine benthic organisms such as foraminifera are still largely overlooked. Here we document the effects of three negatively charged ENM, different in size and composition, titanium dioxide (TiO2), polystyrene (PS) and silicon dioxide (SiO2), on a microbial eukaryote (the benthic foraminifera Ammonia parkinsoniana) using multiple approaches. This research clearly shows the presence, within the foraminiferal cytoplasm, of metallic (Ti) and organic (PS) ENM that promote physiological stress. Specifically, marked increases in the accumulation of neutral lipids and enhanced reactive oxygen species production occurred in ENM-treated specimens regardless of ENM type. This study indicates that ENM represent ecotoxicological risks for this microbial eukaryote and presents a new model for the neglected marine benthos by which to assess natural exposure scenarios.