Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis.
Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis.
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DOI：
10.1016/j.dib.2018.01.005
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发表时间：
2018-04
期刊：
影响因子：
1.2
通讯作者：
Hoppler S
中科院分区：
文献类型：
--
作者：
Afouda BA;Lynch AT;de Paiva Alves E;Hoppler S
转录因子GATA 4、GATA 5和GATA 6在心肌分化中起重要作用。本文中呈现的数据与题为“全基因组转录组学分析将sox7和sox18鉴定为在心肌发生中由gata4特异性调节”的研究文章相关（Afouda等人，2017年）。本研究使用全基因组转录组学分析鉴定了这些单独的心源性加塔因子调控的基因。我们已经展示了由它们中的每一个特异性调控的基因，以及由它们中的任何一个调控的基因。与差异影响的基因相关的基因本体论术语（GO）也被提出。该数据集将允许进一步研究在心肌形成过程中单个心源性加塔因子下游的基因调控网络。
The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (Afouda et al., 2017). The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.