Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus.
Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus.
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成功使用纯大麻二酚治疗超难治性癫痫持续状态。
DOI：
10.1016/j.ebcr.2018.07.004
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发表时间：
2018
影响因子：
--
通讯作者：
Hussain,ShaunA
中科院分区：
文献类型：
--
作者：
Rajaraman,RajsekarR;Sankar,Raman;Hussain,ShaunA
我们提出的情况下，长期的，超难治性癫痫持续状态（SRSE）的儿童谁表现出迅速和完全解决SRSE后，暴露于纯大麻二酚。SRSE出现在远程疑似脑炎的背景下，以前控制良好的癫痫。我们讨论了在何种程度上的反应可能特别归因于大麻二酚，考虑和讨论多种潜在的药物相互作用。基于此，我们建议在SRSE的治疗中考虑抑制性大麻二酚。
We present the case of a child with long-standing, super-refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol. SRSE emerged in the context of remote suspected encephalitis with previously well-controlled epilepsy. We discuss the extent to which response may be specifically attributed to cannabidiol, with consideration and discussion of multiple potential drug–drug interactions. Based on this case, we propose that adjunctive cannabidiol be considered in the treatment of SRSE.