Dual Si-H effects in platinum-catalyzed silane reduction of carboxamides leading to a practical synthetic process of tertiary-amines involving self-encapsulation of the catalyst species into the insoluble silicone resin formed
Dual Si-H effects in platinum-catalyzed silane reduction of carboxamides leading to a practical synthetic process of tertiary-amines involving self-encapsulation of the catalyst species into the insoluble silicone resin formed
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DOI：
10.1016/j.tetlet.2006.06.165
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发表时间：
2006-08-28
影响因子：
1.8
通讯作者：
Nagashima, Hideo
中科院分区：
文献类型：
--
作者：
Hanada, Shiori;Motoyama, Yukihiro;Nagashima, Hideo
发现市售铂催化剂与含有多于两个Si-H基团的硅氧烷的组合是用于将甲酰胺还原成胺的有效催化剂体系。特别是，通过使用聚甲基氢硅氧烷作为还原剂，可以实现从产品中轻松去除硅和铂残留物。(c)2006爱思唯尔有限公司保留所有权利。
Combination of commercially available platinum catalysts with siloxanes containing more than two Si-H groups is found to be an efficient catalyst system for the reduction of carboxamides to amines. In particular, facile removal of silicon and platinum residues from the product can be achieved by the use of polymethylhydrosiloxanes as reducing reagents. (c) 2006 Elsevier Ltd. All rights reserved.