Diet across the Lifespan and the Association with Breast Density in Adulthood.
Diet across the Lifespan and the Association with Breast Density in Adulthood.
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DOI：
10.1155/2013/808317
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发表时间：
2013
影响因子：
1.9
通讯作者：
Hartman T
中科院分区：
文献类型：
--
作者：
Lindgren J;Dorgan J;Savage-Williams J;Coffman D;Hartman T
研究表明，关于饮食因素在女性寿命和乳房密度与乳腺癌之间的关联，结果不一致。乳房密度是乳腺癌的强烈风险因素，其影响癌症风险的机制尚不清楚。乳房密度已经被证明是可以改变的，可能是通过改变饮食。本文的目的是总结目前所有年龄段关于饮食和饮食相关因素的研究，确定哪些饮食因素与乳房密度(最关键的暴露年龄)有最强的相关性，并确定未来的方向。我们确定了28项研究，其中许多是横断面研究，发现绝经前妇女中维生素D、钙、饮食脂肪和酒精之间的相关性最强。重复饮食措施的纵向研究以及随时间推移的整体饮食检查需要证实这些发现。
Studies have shown inconsistent results regarding the association between dietary factors across the lifespan and breast density and breast cancer in women. Breast density is a strong risk factor for breast cancer, and the mechanism through which it influences cancer risk remains unclear. Breast density has been shown to be modifiable, potentially through dietary modifications. The goal of this paper is to summarize the current studies on diet and diet-related factors across all ages, determine which dietary factors show the strongest association with breast density, the most critical age of exposure, and identify future directions. We identified 28 studies, many of which are cross-sectional, and found that the strongest associations are among vitamin D, calcium, dietary fat, and alcohol in premenopausal women. Longitudinal studies with repeated dietary measures as well as the examination of overall diet over time are needed to confirm these findings.