The Cathelicidin Family of Antimicrobial Peptide Precursors: A Component of the Oxygen‐Independent Defense Mechanisms of Neutrophils a
The Cathelicidin Family of Antimicrobial Peptide Precursors: A Component of the Oxygen‐Independent Defense Mechanisms of Neutrophils a
复制标题
DOI：
10.1111/j.1749-6632.1997.tb46244.x
复制
发表时间：
1997-12
影响因子：
5.2
通讯作者：
M. Zanetti;R. Gennaro;D. Romeo
中科院分区：
文献类型：
--
作者：
M. Zanetti;R. Gennaro;D. Romeo
宿主对入侵病原体的保护涉及细胞和体液效应物，并且是非适应性（先天）和适应性（获得性）免疫两者的协同作用的结果。后者基于由克隆分布的受体介导的特异性免疫识别，是免疫系统的新近获得，并且仅存在于脊椎动物中。前者在适应性免疫发展之前就已经进化得很好，由多种细胞和分子组成，
Host protection from invading pathogens involves cellular and humoral effectors and results from the concerted action of both non-adaptive (innate) and adaptive (acquired) immunity. The latter is based on specific immunological recognition mediated by clonally distributed receptors, is a recent acquisition of the immune system, and is present only in vertebrates. The former evolved well before the development of adaptive immunity and consists of a variety of cells and molecules distributed