Prognostic factors in cervical cancer
Prognostic factors in cervical cancer
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DOI：
10.1016/s0301-2115(96)02637-1
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发表时间：
1997-02-01
期刊：
影响因子：
--
通讯作者：
Lahousen, M
中科院分区：
文献类型：
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作者：
Pickel, H;Haas, J;Lahousen, M
临床方法的不足促使人们努力为宫颈癌的扩散和生长行为开发客观、可测量和可重复的参数。首先应用了形态学方法。它们只能用于手术标本，但可用于生物测定。报告的结果基于479例不同大小的宫颈癌根治性腹式子宫切除术的手术标本。标本制作成双侧宫颈、阴道袖带和子宫旁的额部巨大切片。中位随访期为7~8年。在随访数据、生物形态标准和存活率之间发现了统计学上的相关性。有意义的预后因素的统计排序如下：淋巴结转移、淋巴结转移大小、肿瘤体积、宫旁受累和血管侵犯。(C)1997年爱思唯尔爱尔兰科学有限公司。
The inadequacy of clinical methods has spurred efforts to develop objective, measurable and reproducible parameters for the spread and growth behaviour of cervical cancer. Morphological methods were applied first. They can be used only on the surgical specimen, but are accessible to biometry. The presented results are based on 479 surgical specimens obtained at radical abdominal hysterectomy for cervical cancers of different sizes. The specimens were processed as frontal giant sections with the cervix, the vaginal cuff and the parametria on both sides. The median follow-up time was 7-8 years. Statistical correlations were found between follow-up data, biometric morphologic criteria and survival. The statistical ranking of the significant prognostic factors produced the following order: lymph node metastases, size of lymph node metastases, tumour volume, parametrial involvement and vascular invasion. (C) 1997 Elsevier Science Ireland Ltd.