THE ANATOMIC BASIS OF PURE ALEXIA
THE ANATOMIC BASIS OF PURE ALEXIA
复制标题
DOI：
10.1212/wnl.33.12.1573
复制
发表时间：
1983-01-01
期刊：
影响因子：
9.9
通讯作者：
DAMASIO, H
中科院分区：
文献类型：
--
作者：
DAMASIO, AR;DAMASIO, H
对16例单纯失读症患者的行为学和解剖学相关性进行了分析。3例未出现右眼同名偏盲，均为右眼色盲。6例患者出现色泽异常和单侧视神经共济失调。2例患者出现记忆障碍。2例出现视觉失认，无一例出现视觉定向障碍。失读症的关键解剖学关联是左侧枕叶室旁白质的损害，能够损害大脑半球间和半球内的视觉通路。与颜色异常相关的病变位于左侧大脑半球枕颞交界处内侧。
The behavioral and anatomic correlates of pure alexia were analyzed in 16 patients. Right homonymous hemianopia failed to appear in 3 patients, who had right achromatopsia instead. Color anomia and unilateral optic ataxia were seen in 6 patients. Memory defects were found in 2 patients. Visual agnosia was noted in 2. No patient had visual disorientation. The crucial anatomical correlate of alexia was a lesion of the paraventricular white matter of the left occipital lobe, capable of compromising both interhemispheric and intrahemispheric visual pathways. The lesion associated with color anomia was in the mesial occipitotemporal junction of the left hemisphere.