Mycobacteria and Macrophage Apoptosis: Complex Struggle for Survival.

Mycobacteria and Macrophage Apoptosis: Complex Struggle for Survival.
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分枝杆菌和巨噬细胞凋亡:复杂的生存斗争。

DOI:
10.1128/microbe.1.372.1
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发表时间:
2006
期刊:
Microbe (Washington, D.C.)
影响因子:
--
通讯作者:
Early,Julie
Early,Julie
中科院分区:
--
文献类型:
--
作者:
Bermudez,LuizE;Danelishvili,Lia;Early,Julie

文献摘要

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M. avium-infected macrophages undergo apoptosis, but M. tuberculosis suppresses apoptosis and triggers necrosisAlthough distinct, Mycobacterium tuberculosis and Mycobacterium avium both infect and survive in host macrophages. M. tuberculosis is more virulent, specifically adapted to humans, and grows poorly outside of the host. In contrast, M. avium can survive in the environment and also can infect several different host species in addition to humans, including birds, pigs, dogs, and monkeys.