HERITABILITY AND COMPONENTS OF PHENOTYPIC-EXPRESSION IN SKIN REFLECTANCE OF MESTIZOS FROM THE PERUVIAN LOWLANDS
HERITABILITY AND COMPONENTS OF PHENOTYPIC-EXPRESSION IN SKIN REFLECTANCE OF MESTIZOS FROM THE PERUVIAN LOWLANDS
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DOI：
10.1002/ajpa.1330550207
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发表时间：
1981-01-01
影响因子：
2.8
通讯作者：
WAY, A
中科院分区：
文献类型：
--
作者：
FRISANCHO, AR;WAINWRIGHT, R;WAY, A
对 209 名混血儿样本的上臂内侧和前额进行了皮肤反射率测量，样本年龄从 2 岁到 64 岁不等，居住在城镇中，也有秘鲁东部低地的喇嘛。样本包括43对父子、42对父女、62对母子和70对母女。样本还包括57对兄弟、60对姐妹和139对兄弟姐妹。使用型号 670 的光伏反射计进行反射率测量。使用逐步多项式回归技术来导出标准化残差值。使用这些残差值亲代，计算兄弟姐妹类内相关性和皮肤反射率表型表达的组成部分。亲子相关系数和兄弟姐妹相关系数符合多基因遗传假设下预期的理论相关性。夫妻相关性表明肤色的选型交配程度很高，但尽管存在这种影响，亲子和兄弟姐妹的相关系数仍低于常染色体基因影响下的预期值。对遗传力和表型表达成分的估计表明，皮肤反射率总变异的大约 55% 可归因于附加遗传因素的影响。没有证据表明肤色遗传存在X连锁。
Skin reflectance was measured on the inner upper arm and forehead of a sample of 209 Mestizos ranging in age from 2-64 yr living in the town to Lamas in the Eastern Peruvian Lowlands. The sample consisted of 43 father-son, 42 father-daughter, 62 mother-son and 70 mother-daughter pairs. The sample also consisted of 57 brother-brother, 60 sister-sister and 139 brother-sister pairs. The reflectance measurements were made with a Photovolt Reflection Meter, model 670. Stepwise polynomial regression techniques were used to derive standardized residual values. Using these residual values parent-offspring, sibling intraclass correlations and components of the phenotypic expression of skin reflectance were calculated. The parent-offspring and sibling correlation coefficients conformed with the theoretical correlations expected assuming polygenic inheritance. The husband-wife correlations indicate a high degree of assortative mating for skin color, but despite this effect the parent-offspring and sibling correlation coefficients are lower than the values expected under the influence of autosomal genes. Estimates of heritability and components of phenotypic expression indicate that about 55% of the total variability in skin reflectance could be attributed to the influence of the additive genetic factors. There is no evidence of X-linkage in the inheritance of skin color.