Comparative Study of Traditional Single-Needle Electrospinning and Novel Spiral-Vane Electrospinning: Influence on the Properties of Poly(caprolactone)/Gelatin Nanofiber Membranes.
Comparative Study of Traditional Single-Needle Electrospinning and Novel Spiral-Vane Electrospinning: Influence on the Properties of Poly(caprolactone)/Gelatin Nanofiber Membranes.
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传统单针静电纺丝与新型螺旋叶片静电纺丝的对比研究：对聚己内酯/明胶纳米纤维膜性能的影响
DOI：
10.3389/fbioe.2022.847800
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发表时间：
2022
影响因子：
5.7
通讯作者：
Yi B
中科院分区：
文献类型：
--
作者：
Xu Q;Liu W;Yi B
螺旋叶片静电纺丝（SVE）是一种新型的无针静电纺丝技术，被证明可以有效地获得高通量的纳米纤维生产。然而，由SVE生产的静电纺丝纳米纤维的性能仍然相对不足，特别是与传统的单针静电纺丝（SNE）相比。因此，在本研究中，SNE和SVE的比较研究，在制备机制的差异，首先分析使用数值模拟，然后通过实验分析的影响，静电纺聚（己内酯）/明胶（PCL/凝胶）纳米纤维的质量和生物相容性的不同类型。电场强度预测值与实验值吻合较好，表明SVE法制备的PCL/Gel纳米纤维产率高于SNE法。虽然不同的候选人（即，针状和螺旋叶片）对PCL/Gel纳米纤维的表面化学性质、热稳定性和组成影响不大，但对纤维直径分布和力学性能影响较大，其中SVE-静电纺纳米纤维具有较宽的直径分布和较高的柔软性。此外，SVE-电纺纳米纤维也被证明对人脂肪源性干细胞（hADSC）的细胞生长和细胞-纤维相互作用表现出良好的生物相容性。总之，与传统SNE相比，SVE-电纺纳米纤维表现出许多优点，包括高通量产率，良好的透气性和顺应性，这为改善生物医学领域的生物医学应用（例如，组织工程、化妆品和医用纺织品）。
Spiral-vane electrospinning (SVE), a novel needleless electrospinning, was proven effective in obtaining high-throughput production of nanofibers. However, the properties of the electrospun nanofibers produced by SVE remain relatively underexplored, especially in comparison with those made by traditional single-needle electrospinning (SNE). Hence, for the comparative study of SNE and SVE in this study, the difference in the preparation mechanism was first analyzed using numerical simulation, followed by the experimental analysis of the effects of spinneret types on the quality and biocompatibility of electrospun poly(caprolactone)/gelatin (PCL/Gel) nanofibers. The values predicted by the electric field results were consistent with the experimental data, showing that the PCL/Gel nanofibers prepared by SVE have higher yields than SNE. Although the different spinnerets (i.e., needle and spiral vane) had little effect on the surface chemistry, thermal stability, and composition of the PCL/Gel nanofibers, they had great effects on the fiber diameter distribution and mechanical properties in which SVE-electrospun nanofibers have the wider diameter distribution and higher softness. Furthermore, the SVE-electrospun nanofibers were also proven to exhibit good biocompatibility for cell growth of human adipose-derived stem cells (hADSCs) and cell–fiber interactions. Summarily, compared to the traditional SNE, SVE-electrospun nanofibers exhibited many merits including high-throughput yield, good air permeability, and compliance, which provide a facile and effective platform for the improvement of nanofiber applications in biomedical fields (e.g., tissue engineering, cosmetic, and medical textiles).
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影响因子：
6.6
作者：
Wu Y ;Kelly SH ;Sanchez-Perez L ;Sampson JH ;Collier JH
通讯作者：
Collier JH
电场对多针静电纺丝的影响：实验与模拟研究
影响因子：
4.2
作者：
Xie, Sheng;Zeng, Yongchun
通讯作者：
Zeng, Yongchun
影响因子：
2.5
作者：
Gao, Bing;Zuo, Liuyang;Zuo, Baoqi
通讯作者：
Zuo, Baoqi
影响因子：
16.1
作者：
Yin, Jing;Ahmed, Adnan;Xu, Lan
通讯作者：
Xu, Lan
影响因子：
3.2
作者：
Liu, Huan;Zuo, Baoqi
通讯作者：
Zuo, Baoqi