A New Role for Glia in Leptin Action and Energy Balance.

A New Role for Glia in Leptin Action and Energy Balance.
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神经胶质细胞在瘦素作用和能量平衡中的新作用。

DOI:
10.1016/j.cmet.2016.05.020
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发表时间:
2016
期刊:
影响因子:
29
通讯作者:
MyersJr,MartinG
MyersJr,MartinG
中科院分区:
生物学1区
文献类型:
--
作者:
Pan,Warren;MyersJr,MartinG

文献摘要

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针对大脑分裂细胞的化疗或放疗会促进肥胖。Djogo等人(2016)认为,NG2胶质细胞的缺失和中隆起瘦素作用的减弱是这种反应的基础,可能是由于邻近弓状核中树突的缺失。
Chemo- or radiotherapy against dividing cells in the brain can promote obesity. Djogo et al. (2016) suggest that the loss of NG2 glia and diminished leptin action in the median eminence underlie this response, likely due to the loss of dendrites originating in the adjacent arcuate nucleus.