Silk fibroin membrane used for guided bone tissue regeneration
Silk fibroin membrane used for guided bone tissue regeneration
复制标题
丝素蛋白膜用于引导骨组织再生
DOI：
10.1016/j.msec.2016.08.070
复制
发表时间：
2017-01-01
影响因子：
7.9
通讯作者：
Kong, Xiangdong
中科院分区：
文献类型：
--
作者：
Cai, Yurong;Guo, Junmao;Kong, Xiangdong
With the aim to develop a novel membrane with an appropriate mechanical property and degradation rate for guided bone tissue regeneration, lyophilized and densified silk fibroin membrane was fabricated and its mechanical behavior as well as biodegradation property were investigated. The osteoconductive potency of the silk fibroin membranes were evaluated in a defect rabbit calvarial model. Silk fibroin membrane showed the modulated biodegradable and mechanical properties via ethanol treatment with different concentration. The membrane could prevent soft tissue invasion from normal tissue healing, and the amounts of new bone and defect closure with silk fibroin membrane were similar to those of commercially available collagen membrane. (C) 2016 Elsevier B.V. All rights reserved.
