The association of embryonal tumors originating in the kidney and in the brain. A report of seven cases
The association of embryonal tumors originating in the kidney and in the brain. A report of seven cases
复制标题
起源于肾脏和大脑的胚胎肿瘤的关联。
作者：
J. Bonnin;L. J. Rubinstein;N. Palmer;J. Beckwith
该报告记录了 7 名 2 岁以下婴儿的肾胚胎肿瘤（6 名患者为恶性横纹肌样瘤，1 名患者为肾母细胞瘤）与起源于中枢神经系统的胚胎原发性肿瘤之间存在先前未被认识的关联。神经上皮肿瘤包括 3 例小脑髓母细胞瘤、1 例松果体母细胞瘤、1 例原始神经上皮肿瘤（可能是脑神经母细胞瘤）、1 例恶性室管膜下巨细胞星形细胞瘤和 1 例具有不同胶质细胞和神经元分化的小脑髓上皮瘤。没有证据表明这种关联是基于相似组织遗传学或细胞遗传学起源的胚胎细胞的选择性肿瘤转化。这些不同的、胚胎学上无关的肿瘤之间的关系仍然是个谜。
This report documents, in seven infants younger than 2 years of age, a previously unrecognized association of a renal embryonal neoplasm (malignant rhabdoid tumor in six patients and a Wilms' tumor in one) with an embryonal primary tumor originating in the central nervous system. The neuroepithelial tumors included three cerebellar medulloblastomas, one pineoblastoma, one primitive neuroepithelial tumor (probably cerebral neuroblastoma), one malignant subependymal giant cell astrocytoma, and one cerebellar medulloepithelioma with divergent glial and neuronal differentiation. There is no evidence that this association is based on the selective neoplastic transformation of embryonal cells of similar histogenetic or cytogenetic origin. The relationship between these dissimilar, embryologically unrelated tumors remains enigmatic.
肾横纹肌瘤：顺铂和阿霉素诱导完全缓解。
DOI：
10.1002/mpo.2950090211
发表时间：
1981
期刊：
Medical and pediatric oncology
影响因子：
--
作者：
Roper,M;Parmley,RT;Crist,WM;Kelly,DR;Hyland,CH;Salter,M
通讯作者：
Salter,M
肾脏恶性横纹肌样瘤中肌红蛋白的免疫过氧化物酶染色缺失。
DOI：
10.3109/15513818309048287
发表时间：
1983
期刊：
Pediatric pathology
影响因子：
--
作者：
Rutledge,J;Beckwith,JB;Benjamin,D;Haas,JE
通讯作者：
Haas,JE