Biocompatibility of resin-based dental materials applied as liners in deep cavities prepared in human teeth
Biocompatibility of resin-based dental materials applied as liners in deep cavities prepared in human teeth
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DOI：
10.1002/jbm.b.30651
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发表时间：
2007-04-01
影响因子：
3.4
通讯作者：
Hebling, Josimeri
中科院分区：
文献类型：
--
作者：
Alberto de Souza Costa, Carlos;Teixeira, Hilcia Mezzalira;Hebling, Josimeri
背景资料：由于只有少数数据已公布的影响，牙髓牙本质复合体的牙科材料，本研究的目的是评价树脂基材料的生物相容性，适用于内衬在深洞准备在人类牙齿。研究方法：在制备V类洞后，将以下牙科材料应用于轴壁上：第1组，Vitrebond（TM）（VIT; 3 M ESPE）;第2组，Ultra-Blend（（R））Plus（TM）（UBP; Untradent）;和第3组，Clearfil（TM）SE Bond（CSEB; Kuraray）。在第4组（对照）中，使用硬固化氢氧化钙骨水泥Dycal（CH; Caulk/Dentsply）。在临床手术后7天或30 - 85天拔出的牙齿进行组织学评价。结果如下：所有实验组和对照组在第7天的时间内，大多数标本均未出现牙髓反应或轻微的炎症反应，伴有轻微的组织破坏。中度炎症牙髓反应仅发生在第3组的一颗牙齿（RDT = 262 μ m），其中观察到树脂成分的跨牙本质扩散。结论：树脂基牙科粘固剂VIT和UBP以及粘结剂CSEB在健康人牙齿制备的深洞中应用时表现出可接受的生物相容性。(c)2006 Wiley Periodicals，Inc.
Background: Since only a few data have been published concerning the effects of resinous dental materials on the pulp-dentin complex, the aim of this study was to evaluate the biocompatibility of resin-based materials applied as liners in deep cavities prepared in human teeth. Methods: After preparing class V cavities, the following dental materials were applied on the axial walls: group 1, Vitrebond (TM) (VIT; 3M ESPE); group 2, Ultra-Blend((R)) Plus (TM) (UBP; Untradent); and group 3, Clearfil (TM) SE Bond (CSEB; Kuraray). In group 4 (control), the hard-setting calcium hydroxide cement Dycal (CH; Caulk/Dentsply) was used. The teeth extracted at 7 days or between 30 and 85 days after the clinical procedures were processed for histological evaluation. Results: For all the experimental and control groups, most of specimens exhibited no pulpal response or slight inflammatory reaction associated with slight tissue disorganization at 7-day period. Moderate inflammatory pulpal response occurred only in one tooth (RDT = 262 mu m) of group 3 in which transdentinal diffusion of resin components was observed. Conclusion: The resin-based dental cements VIT and UBP as well as the bonding agent CSEB presented acceptable biocompatibility when applied in deep cavities prepared in sound human teeth. (c) 2006 Wiley Periodicals, Inc.