Our interface with the built environment: immunity and the indoor microbiota.

Our interface with the built environment: immunity and the indoor microbiota.
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DOI:
10.1016/j.it.2015.01.001
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发表时间:
2015-03
影响因子:
16.8
通讯作者:
Gilbert JA
Gilbert JA
中科院分区:
医学1区
文献类型:
--
作者:
Lax S;Nagler CR;Gilbert JA

文献摘要

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城市化的兴起和日益室内化的生活方式以前所未有的方式影响了人类与微生物群的相互作用。我们讨论了这种生活方式如何影响免疫发育和功能,并认为现在是我们研究操纵室内环境以增加我们接触更广泛的微生物系统发育的方法的时候了。重要的一步是继续让公民科学家参与研究我们与所居住的不同微生物环境的相互作用的特征。
The rise of urbanization and an increasingly indoor life-style has affected human interactions with our microbiota in unprecedented ways. We discuss how this lifestyle may influence immune development and function, and argue that it is time that we examined ways to manipulate the indoor environment to increase our exposure to a wider phylogeny of microorganisms. An important step is to continue to engage citizen scientists in the efforts to characterize our interactions with the diverse microbial environments that we inhabit.