THE MUSCULUS-TYPE-Y CHROMOSOME OF THE LABORATORY MOUSE IS OF ASIAN ORIGIN
THE MUSCULUS-TYPE-Y CHROMOSOME OF THE LABORATORY MOUSE IS OF ASIAN ORIGIN
复制标题
DOI：
10.1007/bf00431251
复制
发表时间：
1992-01-01
期刊：
影响因子：
2.5
通讯作者：
LAU, YFC
中科院分区：
文献类型：
--
作者：
NAGAMINE, CM;NISHIOKA, Y;LAU, YFC
小家鼠bactrianus，M. m.肌castaneus和M.m.本文研究了蒙古田鼠Y染色体锌指基因（Zfy）和性别决定区基因（Sry）的多态性。Zfy将这些小鼠的Y染色体分为两种类型：肌型（musculus）、栗型（castaneus）和软肌型（molossinus）。M.M. bactrianus标本有两个Y染色体，可能是由于渐渗的肌肉型Y到这个人口。Sry确定了肌肉型Y染色体的亚群。这个亚群，指定的molossin-type，被发现在M. m。molossinus，a M.来自中国北方（长春）的小家鼠亚种标本和实验小鼠。累积数据表明，M. M.中国北方和朝鲜的musculus是一个不同于M.m.的亚群。欧洲和中国中部的musculus，这个亚群入侵日本，引起了M. m。Molossinus。此外，这些数据表明，实验室小鼠的Y型肌肉来源于这个亚群，证实了早期的历史记录，报告说，中国和日本的小鼠进口到欧洲的宠物贸易有助于实验室小鼠的基因组。
Mus musculus domesticus, M.m. bactrianus, M.m. musculus, M.m. castaneus, and M.m. molossinus wild mice were investigated for polymorphisms of the Y Chromosome (Chr) genes Zinc finger-Y (Zfy) and Sex-determining region-Y (Sry). Zfy divided the Y Chrs of these mice into domesticus- (domesticus) and musculus-types (musculus, castaneus, molossinus). M.m. bactrianus specimens had both Y Chrs, possibly owing to the introgression of a musculus-type Y into this population. Sry identified a subpopulation of musculus-type Y chromosomes. This subpopulation, designated the molossinus-type, was found in M.m. molossinus, a M. musculus subspecies specimen from northern China (Changchun), and laboratory mice. The cumulative data suggest that M.m. musculus of northern China and Korea are a subpopulation distinct from M.m. musculus of Europe and central China and that this subpopulation invaded Japan, giving rise to M.m. molossinus. Furthermore, the data suggest that the musculus-type Y of the laboratory mouse originated from this subpopulation, corroborating early historical records reporting that Chinese and Japanese mice that were imported into Europe for the pet trade contributed to the genome of the laboratory mouse.