Subcutaneous Botulinum Toxin for Chronic Post-Thoracotomy Pain
Subcutaneous Botulinum Toxin for Chronic Post-Thoracotomy Pain
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DOI：
10.1111/j.1533-2500.2012.00569.x
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发表时间：
2013-03-01
期刊：
影响因子：
2.6
通讯作者：
De Andres, Jose
中科院分区：
文献类型：
--
作者：
Fabregat, Gustavo;Asensio-Samper, Juan M.;De Andres, Jose
目的：肉毒杆菌毒素是一种神经毒素，广泛用于治疗伴有局限性肌肉痉挛的多种情况下的慢性疼痛。最近的研究表明，肉毒杆菌毒素对治疗带状疱疹后神经痛等神经病理性疼痛综合征有效。病例报告：我们报告一例67岁男性患者，他接受了右下叶肺结节的非典型节段切除术。病人被转诊到我们的疼痛管理科，有两年的持续疼痛病史，沿着开胸疤痕，其主要是神经病变成分，对标准治疗无效。他成功地接受了A型皮下肉毒毒素的治疗。讨论：根据我们自己的经验和对文献中发表的报告的分析，分次皮下注射肉毒毒素可能对治疗各种慢性局部疼痛状况有用，包括开胸手术后的慢性疼痛。
Objective: Botulinum toxin is a neurotoxin that has been widely used in chronic pain for the treatment of multiple conditions with a component of localized muscle spasm. Recent studies suggest that botulinum toxin is effective in the treatment of neuropathic pain syndromes such as post-herpetic neuralgia. Case Report: We report the case of a 67-year-old man who underwent atypical segmentectomy of a right lower lobe lung nodule. The patient was referred to our pain management department with a of 2-year history persistent pain along the thoracotomy scar having a predominantly neuropathic component, refractory to standard treatments. He was successfully treated with subcutaneous botulinum toxin type A. Discussion: On the basics of our own experience and on the analysis of the reports published in the literature, fractioned subcutaneous injections of botulinum toxin may be useful for the treatment of various chronic localized pain conditions including chronic post-thoracotomy pain.