OCULAR DIMENSIONS IN HEREDITY OF ANGLE-CLOSURE GLAUCOMA
OCULAR DIMENSIONS IN HEREDITY OF ANGLE-CLOSURE GLAUCOMA
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DOI：
10.1136/bjo.57.7.475
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发表时间：
1973-01-01
影响因子：
4.1
通讯作者：
LEIGHTON, DA
中科院分区：
文献类型：
--
作者：
TOMLINSON, A;LEIGHTON, DA
目的闭角型青光眼患者眼球的某些解剖学特征是重要的。前房深度（Tornquist，1953）、角膜尺寸、透镜厚度和眼轴长度（Sorsby，谢里丹和Leary，1962; Sorsby和Fraser，1964）由遗传决定。因此，在闭角型青光眼患者和患者的一级亲属中研究这些维度被认为是有意义的。患者及其亲属在这些方面的相似性可以解释这些亲属患上这种疾病的易感性或风险，相反，任何不同之处都可以解释为什么许多亲属没有受到影响，从而阐明了眼部尺寸在闭角型青光眼病因学中的作用。
ObjectivesIt is clear that certain anatomical features of the eyeball are of importance in angle-closure glaucoma. Anterior chamber depth (Tornquist, 1953), corneal dimensions, lens thickness, and axial length (Sorsby, Sheridan, and Leary, I962; Sorsby and Fraser, I964) are genetically determined. It was therefore considered of interest to investigate these dimensions in patients with angle-closure glaucoma and in the first-degree relatives of patients with this condition. A similarity in these dimensions between patients and their relatives may explain a predisposition to, or risk of acquiring, the condition in these relatives, and conversely anydissimilarities many explain why many relatives do not become affected, thus clarifying the role of ocular dimensions in the aetiology of angle-closure glaucoma.