Relationship between nutritional status and frailty in hospitalized older patients
Relationship between nutritional status and frailty in hospitalized older patients
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DOI：
10.2147/cia.s189040
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发表时间：
2019-01-01
影响因子：
3.6
通讯作者：
Chen, Lingyan
中科院分区：
文献类型：
--
作者：
Hong, Xiufang;Yan, Jing;Chen, Lingyan
目的：脆弱的定义尚缺乏定量的生物标志物。本研究旨在探讨营养相关生物标记物与老年住院患者脆弱的关系。材料和方法：这是一项横断面研究，包括380名住院老年患者。按脆弱表型将患者分为非脆弱组140例，早衰组81例，脆弱组159例。采用简明营养评定量表(MNA-SF)、血清转铁蛋白(TNF)、前白蛋白(PA)、总蛋白(TP)、白蛋白(ALB)、视黄醇结合蛋白(RBP)、血红蛋白(Hb)进行营养状况评定。结果：握力、血清TFN、TP、ALB、Hb、MNA-SF评分按非衰弱组、衰弱组、衰弱组依次降低(P
Objective: The definition of frailty still lacks quantitative biomarkers. This study aimed to investigate the relationship between nutrition-related biomarkers and frailty in hospitalized older patients.Materials and methods: This is a cross-sectional study including 380 hospitalized older patients. The patients were categorized as nonfrail (n=140), prefrail (n=81), and frail (n=159) by the criteria of frailty phenotype. The nutritional status was assessed using the mini nutritional assessment-short form (MNA-SF), levels of serum transferrin (TNF), prealbumin (PA), total protein (TP), albumin (ALB), retinol-binding protein (RBP), and hemoglobin (Hb).Results: The grip strength, levels of scrum TFN, TP, ALB, Hb, and MNA-SF scores all decreased significantly in the order of nonfrail, prefrail, and frail groups (P