Topological characteristics of helical repeat proteins
Topological characteristics of helical repeat proteins
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DOI：
10.1016/s0959-440x(99)80052-9
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发表时间：
1999-06-01
影响因子：
6.8
通讯作者：
Barford, D
中科院分区：
文献类型：
--
作者：
Groves, MR;Barford, D
最近对基于重复氨基酸基序的蛋白质结构的研究表明，它们属于螺旋重复蛋白的一类，这些蛋白质的共同特征是由一个α-螺旋结构单元的串联重复组装而成，形成了非常适合于建立蛋白质识别界面的延伸的超螺旋结构。
The recent elucidation of protein structures based upon repeating amino acid motifs, including the armadillo motif, the HEAT motif and tetratricopeptide repeats, reveals that they belong to the class of helical repeat proteins, These proteins share the common property of being assembled from tandem repeats of an alpha-helical structural unit, creating extended superhelical structures that are ideally suited to create a protein recognition interface.