Sociocultural characteristics, obesity and inflammatory biomarkers in Puerto Rican toddlers born in New York City
Sociocultural characteristics, obesity and inflammatory biomarkers in Puerto Rican toddlers born in New York City
复制标题
DOI：
10.1111/pai.12084
复制
发表时间：
2013-08-01
影响因子：
4.4
通讯作者：
Chew, Ginger L.
中科院分区：
文献类型：
--
作者：
Kannan, Srimathi;Acosta, Luis M.;Chew, Ginger L.
背景在美国，波多黎各儿童的哮喘患病率高于其他拉美裔种族，而文化适应是造成这种差异的假设原因之一。我们研究了社会文化特征与2岁儿童血清瘦素、超敏C反应蛋白(HsCRP)和体重指数(BMI)之间的关系，以及hsCRP、瘦素水平、BMI百分位数和过敏致敏之间的关系。方法测定了出生在纽约的波多黎各幼儿(n=143)的血清IgE抗体、瘦素和hsCRP浓度。对母亲、产后和两年后的母亲进行人口统计和家庭特征问卷调查。结果女孩(60%)的瘦素水平高于男孩(37%)(P=0.0063)。瘦素与体重指数呈正相关(r=0.25P=0.0042)。托儿所的儿童更有可能肥胖(40%比24%p
BackgroundIn the USA, Puerto Rican children have a higher prevalence of asthma than other Latino ethnicities, and acculturation is one of hypothesized reasons for this difference. We examined associations between sociocultural characteristics and serum leptin, high-sensitivity C-reactive protein (hsCRP), and body mass index (BMI), and further, among hsCRP, leptin levels, BMI percentiles, and allergic sensitization in 2-year-old children.MethodsIgE antibodies, leptin, and hsCRP concentrations were measured in serum from Puerto Rican toddlers (n=143) born in New York City with a maternal history of allergy and/or asthma. Demographic and home characteristics questionnaires were administered to the mother, postpartum and two years later. Children's weight and height were measured to determine BMI percentiles.ResultsMore girls (60%) had leptin levels above the median compared with boys (37%) (p=0.0063). Leptin was positively correlated with BMI (r=0.25; p=0.0042). Children in daycare were more likely to be obese (40% vs. 24% p