Improved disorder prediction by combination of orthogonal approaches.
Improved disorder prediction by combination of orthogonal approaches.
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DOI:
10.1371/journal.pone.0004433
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发表时间:
2009
期刊:
影响因子:
3.7
通讯作者:
Rost B
中科院分区:
文献类型:
--
作者:
Schlessinger A;Punta M;Yachdav G;Kajan L;Rost B
Disordered proteins are highly abundant in regulatory processes such as transcription and cell-signaling. Different methods have been developed to predict protein disorder often focusing on different types of disordered regions. Here, we present MD, a novel META-Disorder prediction method that molds various sources of information predominantly obtained from orthogonal prediction methods, to significantly improve in performance over its constituents. In sustained cross-validation, MD not only outperforms its origins, but it also compares favorably to other state-of-the-art prediction methods in a variety of tests that we applied. Availability: http://www.rostlab.org/services/md/
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影响因子:
2.9
作者:
Di Lello, P;Benison, GC;Omichinski, JG
通讯作者:
Omichinski, JG
DOI:
10.1107/s0907444906033580
发表时间:
2006-10-01
期刊:
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
影响因子:
--
作者:
Esnouf, Robert M.;Hamer, R.;Prilusky, Jaime
通讯作者:
Prilusky, Jaime
影响因子:
14.9
作者:
Ceroni, Alessio;Passerini, Andrea;Vullo, Alessandro;Frasconi, Paolo
通讯作者:
Frasconi, Paolo
影响因子:
2.9
作者:
Bordoli, Lorenza;Kiefer, Florian;Schwede, Torsten
通讯作者:
Schwede, Torsten
影响因子:
8
作者:
Garbuzynskiy, SO;Lobanov, MY;Galzitskaya, OV
通讯作者:
Galzitskaya, OV