dictyBase:: a new Dictyostelium discoideum genome database
dictyBase:: a new Dictyostelium discoideum genome database
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DOI：
10.1093/nar/gkh138
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Kimmel, AR
中科院分区：
文献类型：
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作者：
Kreppel, L;Fey, P;Kimmel, AR
盘基网柄菌（Dictyostelium discoideum）是一种强大且基因易于操作的模式系统，用于研究众多细胞分子机制，包括趋化性、吞噬作用和信号转导。在过去的两年中，盘基网柄菌的在线资源在范围和可获取性方面有了显著扩展。近期的进展集中在开发一个名为dictyBase（http://dictybase.org）的全新综合在线资源上。该数据库不仅提供对基因组数据的访问，包括基因的功能注释、基因产物和染色体定位，还提供广泛的生物学信息，如突变体表型和相应的参考资料。与来自基因组测序和组装中心的其他网站（http://genome.imb -jena.de/dictyostelium/，http://dictyensembl.bioch.bcm.tmc.edu和http://www.sanger.ac.uk/Projects/D -discoideum/）相结合，这些改进扩大了盘基网柄菌数据库的范围，使其对任何对后生动物比较和功能基因组学感兴趣的研究人员都可获取且有用。
Dictyostelium discoideum is a powerful and genetically tractable model system used for the study of numerous cellular molecular mechanisms including chemotaxis, phagocytosis and signal transduction. The past 2 years have seen a significant expansion in the scope and accessibility of online resources for Dictyostelium. Recent advances have focused on the development of a new comprehensive online resource called dictyBase (http://dictybase.org). This database not only provides access to genomic data including functional annotation of genes, gene products and chromosomal mapping, but also to extensive biological information such as mutant phenotypes and corresponding reference material. In conjunction with additional sites (http://genome. imb-jena.de/dictyostelium/, http://dictyensembl. bioch.bcm.tmc.edu and http://www.sanger.ac.uk/ Projects/D-discoideum/) from the genome sequencing and assembly centers, these improvements have expanded the scope of the Dictyostelium databases making them accessible and useful to any researcher interested in comparative and functional genomics in metazoan organisms.