Mechanism for the unfolding and refolding of ribonuclease A. Simulations using a simple model with no structural intermediates.
Mechanism for the unfolding and refolding of ribonuclease A. Simulations using a simple model with no structural intermediates.
复制标题
核糖核酸酶 A 的展开和重折叠机制。使用没有结构中间体的简单模型进行模拟。
DOI：
10.1021/bi00272a008
复制
发表时间：
1983
期刊：
影响因子：
2.9
通讯作者：
Brandts,JF
中科院分区：
文献类型：
--
作者：
Lin,LN;Brandts,JF
方法用计算机对方程2所描述的模型进行动力学模拟。对于基线重折叠模拟，假设kDN非常大，并且与kDN相比kNO很小。初始分数浓度
MethodsKinetic simulations were carried out for the model depicted in eq 2 by using a computer. For base-line refolding simulations it was assumed that/cDN is very large and that kNO is small compared to &DN. Initial fractional concentrations for