Large Deformation Properties of Red Blood Cell Membrane Based on a Higher Order Gradient Quasi-continuum Model.
Large Deformation Properties of Red Blood Cell Membrane Based on a Higher Order Gradient Quasi-continuum Model.
复制标题
基于高阶梯度准连续模型的红细胞膜大变形特性。
DOI：
10.1007/s00232-015-9809-6
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发表时间：
2015
影响因子：
2.4
通讯作者：
Hu L F
中科院分区：
文献类型：
--
作者：
Wang X Y;Wang J B;Qiu B B;Hu L F
基于所提出的高阶梯度准连续介质模型，数值研究了人红细胞（RBC）膜在室温下大变形（即，300 K）的温度场。结果表明，红细胞膜是一种非线性超弹性材料。红细胞膜的力学性能在初始变形阶段以各向同性为主，但随着载荷的增加，其各向异性材料性能明显显现。数值模拟再现了红细胞膜在剪切载荷作用下的面外变形。利用高阶Cauchy-Born规则作为运动学描述，可以方便地考虑红细胞膜的弯曲刚度。
Based on the proposed higher order gradient quasi-continuum model, the numerical investigations of the basic mechanical properties and deformation behaviors of human red blood cell (RBC) membrane under large deformation at room temperature (i.e., 300 K) are carried out in the present paper. The results show that RBC membrane is a nonlinear hyperelastic material. The mechanical properties of RBC membrane is dominated by isotropic nature at the stage of initial deformation, however, its anisotropic material properties emerge clearly with the loading increasing. The out-of-plane wrinkling of RBC membrane upon shear loading can be reproduced numerically. With the use of the so-called higher order Cauchy–Born rule as the kinematic description, the bending stiffness of RBC membrane can be considered conveniently.