Dry heat and microwave-generated steam protocols for the rapid decontamination of respiratory personal protective equipment in response to COVID-19-related shortages
Dry heat and microwave-generated steam protocols for the rapid decontamination of respiratory personal protective equipment in response to COVID-19-related shortages
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DOI：
10.1016/j.jhin.2020.07.008
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发表时间：
2020-09-01
影响因子：
6.9
通讯作者：
Maillard, J-Y.
中科院分区：
文献类型：
--
作者：
Pascoe, M. J.;Robertson, A.;Maillard, J-Y.
背景资料：在SARS-CoV-2大流行和前所未有的全球需求之后，临床医生正在努力获得足够的个人防护设备。呼吸器可能供应短缺，但对于保护工人免受SARSCoV-2暴露是必要的。快速去污和重复使用的消毒器可以提供缓解紧张的采购situation.Method：在这项研究中，我们调查了70摄氏度的干热和微波产生的蒸汽（MGS）的再处理的FFP 2/N95型消毒器，II型外科口罩的适用性。金黄色葡萄球菌被用作替代物，因为它比包膜病毒对化学和物理过程的敏感性低。金黄色葡萄球菌在70 ° C下干热处理90分钟，并通过MGS减少>6 log（10）90秒。在3个再处理循环后，发现两个过程都不会对测试的澄清器的细菌或NaCl过滤效率产生负面影响。然而，MGS与测试的II型外科口罩不兼容，因为我们证实，再处理后细菌过滤能力完全丧失。由于在某些类型的金属鼻夹周围观察到电弧以及鼻夹与口罩的粘附力丧失，观察到MGS与某些呼吸器类型不兼容。结论：考虑到每种方法的优点和缺点，我们提出了再处理个人防护装备/口罩工作流程用于医疗领域。(C)2020年，卫生保健感染协会。由爱思唯尔有限公司出版。保留所有权利。
Background: In the wake of the SARS-CoV-2 pandemic and unprecedented global demand, clinicians are struggling to source adequate access to personal protective equipment. Respirators can be in short supply, though are necessary to protect workers from SARSCoV-2 exposure. Rapid decontamination and reuse of respirators may provide relief for the strained procurement situation.Method: In this study, we investigated the suitability of 70 degrees C dry heat and microwave-generated steam (MGS) for reprocessing of FFP2/N95-type respirators, and Type-II surgical face masks. Staphylococcus aureus was used as a surrogate as it is less susceptible than enveloped viruses to chemical and physical processes.Results: We observed >4 log(10) reductions in the viability of dry S. aureus treated by dry heat for 90 min at 70 degrees C and >6 log(10) reductions by MGS for 90 s. After 3 reprocessing cycles, neither process was found to negatively impact the bacterial or NaCl filtration efficiency of the respirators that were tested. However, MGS was incompatible with TypeII surgical masks tested, as we confirmed that bacterial filtration capacity was completely lost following reprocessing. MGS was observed to be incompatible with some respirator types due to arcing observed around some types of metal nose clips and by loss of adhesion of clips to the mask.Conclusion: Considering the advantages and disadvantages of each approach, we propose a reprocessing personal protective equipment/face mask workflow for use in medical areas. (C) 2020 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.