Fiber-tracking does not accurately estimate size of fiber bundle in pathological condition: initial neurosurgical experience using neuronavigation and subcortical white matter stimulation
Fiber-tracking does not accurately estimate size of fiber bundle in pathological condition: initial neurosurgical experience using neuronavigation and subcortical white matter stimulation
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DOI：
10.1016/j.neuroimage.2004.07.076
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发表时间：
2005-04-01
期刊：
影响因子：
5.7
通讯作者：
Yoshimine, T
中科院分区：
文献类型：
--
作者：
Kinoshita, M;Yamada, K;Yoshimine, T
这种纤维追踪方法使用扩散张量磁共振成像技术实现了脑白质束的活体可视化。虽然这种方法在神经外科领域代表着一种很有前途的工具，特别是在面对有口才的脑肿瘤时，但其可靠性仍不清楚。在这里，我们通过比较神经导航和脑白质电刺激在两名有口才的脑胶质瘤患者中产生的结果，提出了我们在患有脑肿瘤的受试者中进行脑束成像的初步验证。虽然我们能够用纤维追踪技术可视化锥体束，但图像无法呈现纤维束的实际大小。在这里，我们讨论了纤维跟踪在神经外科领域的优势和局限性。(C)2004 Elsevier Inc.保留所有权利。
The fiber-tracking method enables in vivo visualization of the white matter tracts of the brain using a diffusion tensor MR imaging technique. While this method represents a promising tool in the field of neurosurgery, especially when confronted with brain tumors in eloquent areas, its reliability remains unknown. We present here our preliminary validation of tractography in human subjects harboring brain tumors by comparing the results produced by neuronavigation and electrical white matter stimulation in two patients with gliomas in the eloquent area. Although we were able to visualize the pyramidal tract with the fiber-tracking technique, the images failed to present the actual size of the fiber bundles. Here we discuss the advantages and limitations of fiber-tracking in the field of neurosurgery. (c) 2004 Elsevier Inc. All rights reserved.