Prevalence of primary open-angle glaucoma among patients with obstructive sleep apnea
Prevalence of primary open-angle glaucoma among patients with obstructive sleep apnea
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DOI：
10.1016/j.oooo.2018.01.021
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发表时间：
2018-09-01
影响因子：
2.9
通讯作者：
Giaconi, JoAnn A.
中科院分区：
文献类型：
--
作者：
Friedlander, Arthur H.;Graves, Lindsay L.;Giaconi, JoAnn A.
客观的。我们的目的是确定阻塞性睡眠呼吸暂停 (OSA) 患者中原发性开角型青光眼 (POAG) 的患病率，因为围手术期环境有进一步损害视神经的风险。研究设计。由于持续气道正压通气不耐受，我们分析了睡眠医学协会推荐的用于口腔矫治器的“方便样本”。我们确定了指标人群中 3 种 POAG 亚型——“经典”开角型青光眼 (COAG)、正常眼压性青光眼 (NTG) 和疑似开角型青光眼 (OAGS) 的总患病率，并将其与同一医院的一般人群进行比较。同样确定了 OSA 严重程度（呼吸暂停低通气指数 [AHI]）和 POAG 亚型之间的关联。结果。在 225 名 OSA 患者的研究样本中（96.4% 为男性；平均年龄 58.5 +/- 12.3 岁），47 名（20.9%）患有 POAG，亚型分布为 COAG：12（25.5%）、NTG：8（17.0%）和 OAGS：27（57.4%）。医疗中心一般人群POAG患病率为2.5%，显着较低(P<0.05)。结论。 POAG 在 OSA 患者中的显着患病率表明需要眼科医生进行术前咨询以确定眼睛健康状况，并可能需要麻醉师进行咨询以避免潜在的视力丧失。
Objective. Our objective was to determine primary open-angle glaucoma (POAG) prevalence among obstructive sleep apnea (OSA) patients because the perioperative environment risks further damaging the optic nerve.Study Design. We analyzed a "convenience sample" referred by Sleep Medicine for oral appliances because of continuous positive airway pressure intolerance. We determined the aggregate prevalence of the 3 POAG subtypes-"classic" open-angle glaucoma (COAG), normal-tension glaucoma (NTG), and open-angle glaucoma suspect (OAGS)-among the index population and compared it with that of same hospital's general population. Similarly determined were associations between OSA severity levels (apnea-hypopnea index [AHI]) and POAG subtypes.Results. Among the study sample of 225 patients with OSA (96.4% male; mean age 58.5 +/- 12.3 years), 47 (20.9%) had POAG, with a subtype distribution of COAG: 12 (25.5%), NTG: 8 (17.0%), and OAGS: 27 (57.4%). The POAG prevalence rate among medical center's general population was 2.5%, which was significantly less (P .05).Conclusion. The significant prevalence of POAG among OSA sufferers suggests need for preoperative consultations from an ophthalmologist to determine eye health and possibly an anesthesiologist to avoid potential vision loss.