Behavioral analysis after sciatic nerve compression in albino rats
Behavioral analysis after sciatic nerve compression in albino rats
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DOI：
10.5214/ans.0972.7531.1118203
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发表时间：
2011-04-01
影响因子：
1.5
通讯作者：
Babu, R. Suresh
中科院分区：
文献类型：
--
作者：
Anand, P.;Mathangi, D. C.;Babu, R. Suresh
背景：步行轨迹分析已被广泛用于检测坐骨神经损伤大鼠步态功能的恢复。目的：本研究的目的是客观地分析和量化大鼠坐骨神经挤压伤后运动行为的功能恢复程度。方法：Wistar大鼠在各种跑道上训练，即，窄梁、网格和楼梯，随后在坐骨神经挤压损伤后进行测试。结果如下：损伤大鼠在跑道上的运动能力逐渐恢复，至术后第6周与术前相比无显著差异。结论：常规跑道可客观地用于定量回收水平。
Background: Walking track analysis which has been widely used to examine the recovery of gait functions in rats with sciatic nerve injury. Purpose: The present study was aimed to objectively analyze and quantify the degree of functional recovery in locomotor behavior of rats after inflicting sciatic nerve crush injury. Methods: Wistar rats trained on various runways, viz., narrow beam, grid and staircase, were subsequently tested following sciatic nerve crush injury. Results: Locomotor ability of injured rats on runways gradually recovered to the level that was not significantly different from their corresponding preoperative level by the sixth postoperative week. Conclusion: Conventional run ways can be objectively used for quantification of the level of recovery.