Anti-Ro/SSA-antibodies and heart rhythm disturbances in the general population: the 'dark side of the immune'.
Anti-Ro/SSA-antibodies and heart rhythm disturbances in the general population: the 'dark side of the immune'.
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一般人群中的抗 Ro/SSA 抗体和心律失常：“免疫的阴暗面”。
DOI：
10.1093/eurheartj/ehac575
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发表时间：
2022
影响因子：
39.3
通讯作者：
Capecchi,PierLeopoldo
中科院分区：
文献类型：
--
作者：
Lazzerini,PietroEnea;Boutjdir,Mohamed;Capecchi,PierLeopoldo
抗Ro/SSA抗体对普通人群心律失常风险的影响及潜在机制QTc，校正的QT间期; ICaL，L型钙电流; AP，动作电位; hERG-K+，人类ether-a-go-go相关基因钾通道; IKr，延迟整流钾电流的快速成分; APD，动作电位时程。本文表达的观点不一定是《欧洲心脏杂志》或欧洲心脏病学会编辑的观点。*通讯作者。电话：+ 39 0577 5585743;传真：+ 39 0577 233318;电子邮件：lazzerini7@unisi。这些作者对这项工作的贡献是相等的。
Impact of anti-Ro/SSA-antibodies on cardiac arrhythmia risk in the general population and putative underlying mechanisms. QTc, corrected QT interval; ICaL, L-type calcium current; AP, action potential; hERG-K+, human ether-a-go-go-related gene potassium channel; IKr, rapid component of the delayed rectifier potassium current; APD, action potential duration.The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.* Corresponding author. Tel:+ 39 0577 5585743; Fax+ 39 0577 233318; Email: lazzerini7@ unisi. it† These authors contributed equally to this work.