Electrical stimulation in the medullary nucleus raphe magnus inhibits noxious heat-evoked fos protein-like immunoreactivity in the rat lumbar spinal cord.
Electrical stimulation in the medullary nucleus raphe magnus inhibits noxious heat-evoked fos protein-like immunoreactivity in the rat lumbar spinal cord.
复制标题
中缝大髓核的电刺激抑制大鼠腰脊髓中有害的热诱发的 fos 蛋白样免疫反应性。
DOI：
10.1016/0006-8993(90)91306-2
复制
发表时间：
1990
期刊：
影响因子：
2.9
通讯作者：
Light,AR
中科院分区：
文献类型：
--
作者：
Jones,SL;Light,AR
Noxious heat applied to the footpad evokes the expression offosprotein-like immunoreactivity in the rat spinal cord lumbar dorsal horn. Electrical stimulation in the medullary nucleus raphe magnus (NRM) while not evokingfos-like immunoreactivity itself, reduced significantly the number of neurons (to 50% of control) in the dorsal horn demonstratingfosprotein-like immunoreactivity in response to noxious heating of the footpad. Thus descending projections from the medullary NRM appear to have direct inhibitory effects on dorsal horn neurons that receive nociceptive input from cutaneous thermal nociceptors.
