Letter by Hu et al Regarding Article, "Modernized Classification of Cardiac Antiarrhythmic Drugs"
Letter by Hu et al Regarding Article, "Modernized Classification of Cardiac Antiarrhythmic Drugs"
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胡等人关于文章“心脏抗心律失常药物的现代化分类”的信
DOI：
10.1161/circulationaha.118.038831
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发表时间：
2019
期刊：
影响因子：
37.8
通讯作者：
Huang Congxin
中科院分区：
文献类型：
--
作者：
Hu Dan;Huang Yan;Huang Congxin
The classification of antiarrhythmic drugs (AADs) was proposed by Vaughan Williams 1 and supplemented by other researchers. This classification assigns drugs to 4 categories based on the electrophysiological characteristics of their actions. Since their introduction in 1970, AADs are still widely recognized and used in clinical practice. However, as time goes on, more novel AADs appear, and the mechanisms are being well explored, but they are still incomplete. Therefore, the classification of AADs needs to be more precise.To commemorate the centennial anniversary of Professor Vaughan Williams’s birth, Lei and colleagues 2 redefined the AADs as 8 classes, including 32 types, which will greatly advance treatment decision in current clinical practice and help develop new AADs in the future. This new classification summarized the progress of AADs over the past half century, covered all the major mechanisms known currently, included specific electrophysiological targets associated with cardiac electrophysiology, and will provide valuable guidance for our understanding of arrhythmia and AADs.
