Transmission of a Y chromosomal deletion involving the deleted in azoospermia (DAZ) and chromodomain (CDY1) genes from father to son through intracytoplasmic sperm injection
Transmission of a Y chromosomal deletion involving the deleted in azoospermia (DAZ) and chromodomain (CDY1) genes from father to son through intracytoplasmic sperm injection
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DOI：
10.1093/humrep/14.9.2320
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发表时间：
1999-09-01
影响因子：
6.1
通讯作者：
Nieschlag, E
中科院分区：
文献类型：
--
作者：
Kamischke, A;Gromoll, J;Nieschlag, E
据报道，在胞浆内单精子注射 (ICSI) 治疗后，严重少精子症患者的无精子症 (DAZ) 缺失遗传给了他的儿子。该病例报告强调了接受 ICSI 治疗的患者携带 Y 染色体缺失的精子的受精能力，并强调了遗传咨询在严重男性不育症中的重要性。
The transmission of a deleted in azoospermia (DAZ) deletion from a severely oligozoospermic patient to his son following intracytoplasmic sperm injection (ICSI) treatment is reported. The case report highlights the fertilizing capacity of spermatozoa carrying Y chromosome deletions in patients treated with ICSI and stresses the importance of genetic counselling in severe male infertility.