The evaluation of screening for gastric cancer in miyagi prefecture, Japan: A population‐based case‐control study
The evaluation of screening for gastric cancer in miyagi prefecture, Japan: A population‐based case‐control study
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日本宫城县胃癌筛查评估：基于人群的病例对照研究
DOI：
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发表时间：
1995
影响因子：
6.4
通讯作者：
A. Takano
中科院分区：
文献类型：
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作者：
A. Fukao;Y. Tsubono;I. Tsuji;S. Hisamichi;N. Sugahara;A. Takano
虽然在过去的30年里，日本广泛开展了使用钡X射线检查的胃癌筛查计划，但没有足够的证据证实其在降低死亡率方面的有效性。为了评价筛查的有效性，在日本宫城县进行了一项基于人群的病例对照研究。从国民健康保险成员中选择死于胃癌的病例受试者（198例）和年龄、性别和居住地相匹配的对照受试者（577例）。根据地区癌症登记处和癌症检测中心的记录，调查了病例诊断前5年内的筛查史。5年内至少参加过一次筛查的人死于胃癌的比值比（OR）为0.41。对于那些在5年内只参加过一次的人来说，OR为0.43，而对于那些最后一次参加是在5年前的人来说，OR为0.30。我们的数据表明，每隔5年进行一次胃癌筛查可能会使死亡率降低60%，而且这种效果可能会持续至少5年。© 1995 Wiley利斯公司
Although a screening program for gastric cancer, using barium X‐ray examination, has been carried out widely in Japan for the past 3 decades, there is insufficient evidence to confirm its effectiveness in terms of reducing mortality. To evaluate the effectiveness of the screening, a population‐based case‐control study was carried out in Miyagi Prefecture, japan. Case subjects, who had died from gastric cancer (198) and control subjects matched in age, sex and residence (577) were selected from among members of the National Health Insurance. Their screening histories during 5 years before the cases were diagnosed were surveyed on the basis of records of the regional cancer registry and the cancer‐detection center. The odds ratio (OR) of death from gastric cancer for the persons who participated in the screening at least once during 5 years was 0.41. For those who participated only once during 5 years the OR was 0.43, and for those whose last participation was 5 years earlier it was 0.30. Our data suggest that screening for gastric cancer at 5‐year intervals might reduce mortality by 60%, and that the effect might remain for at least 5 years. © 1995 Wiley‐Liss, Inc.