An Enantioselective Synthesis of (R)- and (S)-4,5-Dimethyl-4-hexanolides —— Key Intermediates for 2,3-Dihydro-2-isopropyl-2,5-dimethylfuran, a Sex Specific Compounds in Females of the Beetle Hylecoetus dermestoides L.
An Enantioselective Synthesis of (R)- and (S)-4,5-Dimethyl-4-hexanolides —— Key Intermediates for 2,3-Dihydro-2-isopropyl-2,5-dimethylfuran, a Sex Specific Compounds in Females of the Beetle Hylecoetus dermestoides L.
复制标题
(R)-和(S)-4,5-二甲基-4-己内酯的对映选择性合成——女性性别特异性化合物2,3-二氢-2-异丙基-2,5-二甲基呋喃的关键中间体甲虫 Hylecoetus dermestoides L.
DOI：
10.3987/com-91-s99
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发表时间：
1992
期刊：
影响因子：
0.6
通讯作者：
K. Fukumoto*
中科院分区：
文献类型：
--
作者：
H. Nemoto;H. Ishibashi;K. Fukumoto*
两种对映体 (R)- 和 (S)-4,5-二甲基-4-己内酯 (11) 都是通过环丙叉乙醇 (7) 的串联不对称环氧化和对映特异性 1,2-重排作为关键反应合成的
Both the enantiomers, (R)- and (S)-4,5-dimethyl-4-hexanolides (11), were synthesized via tandem asymmetric epoxidation and enantiospecific 1,2-rearrangement of cyclopropylideneethanol (7) as a key reaction