Alkyne as a spectator ligand for the nickel-catalyzed multicomponent connection reaction of diphenylzinc, 1,3-butadiene, aldehydes, and amines
Alkyne as a spectator ligand for the nickel-catalyzed multicomponent connection reaction of diphenylzinc, 1,3-butadiene, aldehydes, and amines
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DOI：
10.1021/ol0703480
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发表时间：
2007-05-10
期刊：
影响因子：
5.2
通讯作者：
Tamaru, Yoshinao
中科院分区：
文献类型：
--
作者：
Kimura, Masanari;Tatsuyama, Yasushi;Tamaru, Yoshinao
在镍催化下，在3-己炔存在下，芳香胺的醛与Ph_2Zn和一分子丁二烯反应生成1，而脂肪胺的醛与Ph_2Zn和两个丁二烯反应生成2，其中3-己炔作为旁观配体控制1和2的选择性生成。
Under nickel catalysis, in the presence of 3-hexyne, the aldimines of aromatic amines react with Ph2Zn and one molecule of butadiene to provide 1 exclusively, while the aldimines of aliphatic amines react with Ph2Zn and two molecules of butadiene to provide 2 exclusively, where 3-hexyne serves as a spectator ligand controlling the selective formation of 1 and 2.