Cortical mechanism of communicative speech production
Cortical mechanism of communicative speech production
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DOI：
10.1016/j.neuroimage.2007.05.059
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发表时间：
2007-09-01
期刊：
影响因子：
5.7
通讯作者：
Kawashima, Ryuta
中科院分区：
文献类型：
--
作者：
Sassa, Yuko;Sugiura, Motoaki;Kawashima, Ryuta
交际性言语不仅要求遵守语言规则，而且要求遵守适合社会交往的行为。自闭症患者的社交障碍研究表明，大脑中存在一种特殊的机制来控制交际言语的行为方面，这种机制可能与动物的交际发声有关。我们使用功能性磁共振成像（fMRI）来测量正常受试者在与演员随意交谈（交流任务）或口头描述一种情况（描述任务）时的皮层激活情况，同时观察熟悉或不熟悉的演员在典型日常情况下的动作视频剪辑。我们假设交际任务与描述任务的不同之处在于涉及交际言语产生的行为方面，这可能涉及与互动相关的传记信息的处理。在交流任务中，大脑内侧前额叶皮层（极部和背部）、双侧颞前上沟和左颞顶叶交界处的激活明显高于描述任务。结果表明，这些区域在交际言语产生的行为方面发挥作用，可能在理解社会互动的背景方面。在交际任务中，演员熟悉时，内侧前额叶皮层极区比演员不熟悉时更活跃，这表明该区域参与参照生物信息的交际言语产生。楔前叶仅在与熟悉的参与者进行交流时才被激活，这表明该区域与获取传记信息本身有关。(c) 2007爱思唯尔公司版权所有。
Communicative speech requires conformity not only to linguistic rules but also to behavior that is appropriate for social interaction. The existence of a special brain mechanism for such behavioral aspects of communicative speech has been suggested by studies of social impairment in autism, and it may be related to communicative vocalization in animals. We used functional magnetic resonance imaging (fMRI) to measure cortical activation while normal subjects casually talked to an actor (communication task) or verbally described a situation (description task) while observing video clips of an action performed by a familiar or an unfamiliar actor in a typical daily situation. We assumed that the communication task differed from the description task in the involvement of behavioral aspects of communicative speech production, which may involve the processing of interaction-relevant biographical information. Significantly higher activation was observed during the communication task than during the description task in the medial prefrontal cortex (polar and dorsal parts), the bilateral anterior superior temporal sulci, and the left temporciparietal junction. The results suggest that these regions play a role in the behavioral aspects of communicative speech production, presumably in understanding of the context of the social interaction. The activation of the polar part of the medial prefrontal cortex during the communication task was greater when the actor was familiar than when the actor was unfamiliar, suggesting that this region is involved in communicative speech production with reference to biological information. The precuneus was activated during the communication task only with the familiar actor, suggesting that this region is related to access to biographical information per se. (c) 2007 Elsevier Inc. All rights reserved.