Mutagenicity evaluation of chemical pesticides.
Mutagenicity evaluation of chemical pesticides.
复制标题
化学农药致突变性评价。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
M. Waters
中科院分区：
文献类型：
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作者：
S. Sandhu;M. Waters
在过去的几十年里，化学农药的使用量在美国急剧增加。这种相对突然的增加令美国环境保护局(EPA)非常担忧，因为它有责任确保在美国使用的所有杀虫剂的安全。为了回应这种担忧，EPA建立了一个审查计划，即可推翻的注册推定(RPAR)，用于定期重新评估农药化合物的诱变和致癌潜力。本文对6种化学农药致突变性的文献报道进行了综述和评价。所讨论的农药化学品是顺丁烯二酸肼、鱼藤酮、吗草隆、二没食子酸酯、三没食子酸酯和苯菌灵。
Over the last few decades, the use of chemical pesticides has increased dramatically in the U.S. This relatively sudden increase greatly concerns the U.S. Environmental Protection Agency (EPA), since it has the responsibility for ensuring the safety of all pesticides used in the U.S. In response to this concern, EPA has established a review program, the Rebuttable Presumption Against Registration (RPAR), for periodically reassessing the mutagenic and carcinogenic potential of pesticide compounds. This paper presents a review and evaluation of the data reported in the literature on six chemical pesticides suspect for mutagenic potential. The pesticide chemicals discussed are maleic hydrazide; rotenone; monuron; diallate; triallate, and benomyl.