Factors predisposing women to chronic pelvic pain: systematic review

Factors predisposing women to chronic pelvic pain: systematic review
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DOI:
10.1136/bmj.38748.697465.55
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发表时间:
2006-04-01
影响因子:
105.7
通讯作者:
Khan, K
Khan, K
中科院分区:
医学1区
文献类型:
--
作者:
Latthe, P;Mignini, L;Khan, K

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目的评估诱发妇女慢性和复发性盆腔疼痛的因素。设计、数据来源和方法通过Medline、Embase、PsycINFO、科克伦图书馆、SCISESTUDIO、会议论文和检索到的主要和综述文章的参考书目,对相关研究进行系统回顾,无语言限制。两名评审员独立提取蛤蜊油研究特征、质量和结果。比较了有和没有盆腔疼痛的妇女暴露于危险因素的情况。结果汇总内定义的疼痛类型和危险factors.Results的亚组有122项研究(111篇文章),其中63(64 286名妇女)评价54个危险因素的痛经,19(18 601名妇女)评价14个危险因素性交困难,40(12 040名妇女)评价48个因素的非周期性盆腔疼痛。年龄< 30岁、体重指数低、吸烟、月经初潮早(< 12岁)、月经周期长、月经量大、无产、经前综合征、绝育、临床疑似盆腔炎、性虐待和心理症状与痛经有关。第一次分娩时年龄较小,运动和口服避孕药与痛经呈负相关。绝经、盆腔炎、性虐待、焦虑和抑郁与性交困难有关。药物或酒精滥用,流产,月经量大,盆腔炎,以前的剖腹产,盆腔病理,滥用,和心理共病与所有非周期性盆腔疼痛的风险增加。结论几个妇科和心理社会因素与慢性盆腔疼痛密切相关。需要针对这些潜在可改变因素进行干预的随机对照试验,以评估其在慢性盆腔疼痛中的临床相关性。
Objective To evaluate factors predisposing women to chronic and recurrent pelvic pain.Design, data sources, and methods Systematic review Of relevant studies without language restrictions identified through Medline, Embase, PsycINFO, Cochrane Library, SCISEARCH, conference papers, and bibliographies of retrieved primary and review articles. Two reviewers independently extracted clam Oil study characteristics, quality and results.. Exposure to risk factors was compared between women with and without pelvic pain. Results were pooled within subgroups defined by type of pain and risk factors.Results There were 122 studies (in 111 articles) of which 63 (in 64 286 women) evaluated 54 risk factors for dysmenorrhoea, 19 (in 18 601 women) evaluated 14 risk factors for dyspareunia, and 40 (in 12 040 women) evaluated 48 factors for non-cyclical pelvic pain. Age < 30 years, low body mass index, smoking, earlier menarche (< 12 years), longer cycles, heavy menstrual flow, nullliparity, premenstrual syndrome, sterilisation, clinically suspected pelvic inflammatory disease, sexual abuse, and psychological symptoms were associated with dysmenorrhoea. Younger age at first childbirth, exercise, and oral contraceptives were negatively associated with dysmenorrhoea. Menopause, pelvic inflammatory disease, sexual abuse, anxiety, and depression were associated with dyspareunia. Drug Or alcohol abuse, miscarriage, heavy menstrual flow, pelvic inflammatory disease, previous caesarean section, pelvic pathology, abuse, and psychological comorbidity were associated with all increased risk of non-cyclical pelvic pain.Conclusion Several gynaecological and psychosocial factors are strongly associated with chronic pelvic pain. Randomised controlled trials of interventions targeting these potentially modifiable factors are needed to assess their clinical relevance in chronic pelvic pain.