First Trimester Serum 25-Hydroxyvitamin D Status and Factors Related to Lower Levels in Gravids Living in the Spanish Mediterranean Coast
First Trimester Serum 25-Hydroxyvitamin D Status and Factors Related to Lower Levels in Gravids Living in the Spanish Mediterranean Coast
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DOI：
10.1177/1933719110396720
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发表时间：
2011-08-01
影响因子：
2.9
通讯作者：
Chedraui, Peter
中科院分区：
文献类型：
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作者：
Perez-Lopez, Faustino R.;Fernandez-Alonso, Ana M.;Chedraui, Peter
目的：评估西班牙孕妇妊娠早期血清25-羟基维生素D [25(OH)D]水平及缺乏相关因素。方法：对生活在西班牙地中海沿岸（北纬36度，西经2度）阿尔梅里亚附近的502例11 ~ 14周孕妇进行横断面研究，采用电化学发光免疫分析法测定血清25(OH)D水平。采用Logistic和多元线性回归分析来评估种族、移民身份、采血季节、体重指数（BMI）、胎次和吸烟习惯对25(OH)D水平的影响。结果：整个样本的血清25(OH)D水平中位数（四分位数范围，IQR）为27.4 ng/mL （IQR为20.9-32.8）。只有35.9%的参与者有足够的血清25(OH)D水平（bb0 = 30 ng/mL），而41.4%和22.7%的参与者发现这些水平不足（20-29.9 ng/mL）和缺乏(
Objective: To assess first trimester serum 25-hydroxyvitamin D [25(OH)D] status and factors related to deficient levels in pregnant Spanish women. Methods: This cross-sectional study was carried out among 502 gravids (11 to 14 weeks) living in the Spanish Mediterranean sea coast (near Almeria at latitude 36 degrees N, longitude 2 degrees W) to whom serum 25(OH)D levels were measured by electrochemiluminescence immunoassay. Logistic and multiple linear regression analysis were performed to assess the influence of ethnicity, immigration status, season of the year at blood sampling, body mass index (BMI), parity and smoking habit over 25(OH)D levels. Results: The median (interquartile range, IQR) serum 25(OH)D levels for the entire sample was 27.4 ng/mL (IQR 20.9-32.8). Only 35.9% of participants had adequate serum 25(OH)D levels (>= 30 ng/mL) whereas in 41.4% and 22.7% these levels were found to be insufficient (20-29.9 ng/mL) and deficient (