Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride
Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride
复制标题
OCT2 和 MATE1 在氯化两面针的肾脏处置和毒性中的作用
DOI:
10.1111/bph.13537
复制
发表时间:
2016-08-01
影响因子:
7.3
通讯作者:
Jiang, H. D.
中科院分区:
文献类型:
--
作者:
Li, L. P.;Song, F. F.;Jiang, H. D.
Nitidine chloride (NC), a benzophenanthridine alkaloid, has various biological properties including anticancer and analgesic activities. The aim of the present study was to evaluate the role of organic cation transporter 2 (OCT2) and multidrug and toxin extrusion 1 (MATE1) in the renal disposition and nephrotoxicity of NC.